Interleukin-6 regulates the zinc transporter Zip14 in liver and contributes to the hypozincemia of the acute-phase response

Infection and inflammation produce systemic responses that include hypozincemia and hypoferremia. The latter involves regulation of the iron transporter ferroportin 1 by hepcidin. The mechanism of reduced plasma zinc is not known. Transcripts of the two zinc transporter gene families (ZnT and Zip) w...

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Bibliographic Details
Main Authors: Liuzzi, Juan P., Lichten, Louis A., Rivera, Seth, Blanchard, Raymond K., Aydemir, Tolunay Beker, Knutson, Mitchell D., Ganz, Tomas, Cousins, Robert J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1100791/
https://ncbi.nlm.nih.gov/pubmed/15863613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502257102
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