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Hepatic ZIP14-mediated Zinc Transport Contributes to Endosomal Insulin Receptor Trafficking and Glucose Metabolism

Zinc influences signaling pathways through controlled targeted zinc transport. Zinc transporter Zip14 KO mice display a phenotype that includes impaired intestinal barrier function with low grade chronic inflammation, hyperinsulinemia, and increased body fat, which are signatures of diet-induced dia...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Aydemir, Tolunay Beker, Troche, Catalina, Kim, Min-Hyun, Cousins, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5104920/
https://ncbi.nlm.nih.gov/pubmed/27703010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.748632
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