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Interleukin-1β contributes via nitric oxide to the upregulation and functional activity of the zinc transporter Zip14 (Slc39a14) in murine hepatocytes

Zinc metabolism during chronic disease is dysregulated by inflammatory cytokines. Experiments with IL-6 knockout mice show that LPS regulates expression of the zinc transporter, Zip14, by a mechanism that is partially independent of IL-6. The LPS-induced model of sepsis may occur by a mechanism sign...

詳細記述

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書誌詳細
主要な著者: Lichten, Louis A., Liuzzi, Juan P., Cousins, Robert J.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670674/
https://ncbi.nlm.nih.gov/pubmed/19179618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90676.2008
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