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Interleukin-1β contributes via nitric oxide to the upregulation and functional activity of the zinc transporter Zip14 (Slc39a14) in murine hepatocytes

Zinc metabolism during chronic disease is dysregulated by inflammatory cytokines. Experiments with IL-6 knockout mice show that LPS regulates expression of the zinc transporter, Zip14, by a mechanism that is partially independent of IL-6. The LPS-induced model of sepsis may occur by a mechanism sign...

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Detalhes bibliográficos
Main Authors: Lichten, Louis A., Liuzzi, Juan P., Cousins, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670674/
https://ncbi.nlm.nih.gov/pubmed/19179618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90676.2008
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