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Mechanical unfolding of RNA hairpins

Mechanical unfolding trajectories, generated by applying constant force in optical-tweezer experiments, show that RNA hairpins and the P5abc subdomain of the group I intron unfold reversibly. We use coarse-grained Go-like models for RNA hairpins to explore forced unfolding over a broad range of temp...

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Bibliografske podrobnosti
Main Authors: Hyeon, Changbong, Thirumalai, D.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1100749/
https://ncbi.nlm.nih.gov/pubmed/15749822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408314102
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