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Iterative annealing mechanism explains the functions of the GroEL and RNA chaperones

Molecular chaperones are ATP‐consuming machines, which facilitate the folding of proteins and RNA molecules that are kinetically trapped in misfolded states. Unassisted folding occurs by the kinetic partitioning mechanism according to which folding to the native state, with low probability as well a...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Thirumalai, D., Lorimer, George H., Hyeon, Changbong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954723/
https://ncbi.nlm.nih.gov/pubmed/31800116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3795
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