Structure-Based Mutational Analysis of the C-Terminal DNA-Binding Domain of Human Immunodeficiency Virus Type 1 Integrase: Critical Residues for Protein Oligomerization and DNA Binding

The C-terminal domain of human immunodeficiency virus type 1 (HIV-1) integrase (IN) is a dimer that binds to DNA in a nonspecific manner. The structure of the minimal region required for DNA binding (IN(220–270)) has been solved by nuclear magnetic resonance spectroscopy. The overall fold of the C-t...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	J Virol
Päätekijät:	Lutzke, Ramon A. Puras, Plasterk, Ronald H. A.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	American Society for Microbiology (ASM) 1998
Aiheet:	Animal Viruses
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110031/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9573250/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.6.4841-4848.1998
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