Učitavanje...
Alanine Substitutions of Polar and Nonpolar Residues in the Amino-Terminal Domain of CCR5 Differently Impair Entry of Macrophage- and Dualtropic Isolates of Human Immunodeficiency Virus Type 1
Multiple extracellular domains of the CC-chemokine receptor CCR5 are important for its function as a human immunodeficiency virus type 1 (HIV-1) coreceptor. We have recently demonstrated by alanine scanning mutagenesis that the negatively charged residues in the CCR5 amino-terminal domain are essent...
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Glavni autori: | , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
American Society for Microbiology
1998
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC109856/ https://ncbi.nlm.nih.gov/pubmed/9525683 |
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