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Evidence of a Role for Phosphatidylinositol 3-Kinase Activation in the Blocking of Apoptosis by Polyomavirus Middle T Antigen

A polyomavirus mutant (315YF) blocked in binding phosphatidylinositol 3-kinase (PI 3-kinase) has previously been shown to be partially deficient in transformation and to induce fewer tumors and with a significant delay compared to wild-type virus. The role of polyomavirus middle T antigen-activated...

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Détails bibliographiques
Auteurs principaux: Dahl, Jean, Jurczak, Annmarie, Cheng, Linda A., Baker, David C., Benjamin, Thomas L.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC109788/
https://ncbi.nlm.nih.gov/pubmed/9525648
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