Attenuation of Influenza A Virus mRNA Levels by Promoter Mutations

We have engineered influenza A/WSN/33 viruses which have viral RNA (vRNA) segments with altered base pairs in the conserved double-stranded region of their vRNA promoters. The mutations were introduced into the segment coding for the neuraminidase (NA) by using a reverse genetics system. Two of the...

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Detalles Bibliográficos

Publicado en:	J Virol
Autores principales:	Fodor, Ervin, Palese, Peter, Brownlee, George G., García-Sastre, Adolfo
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1998
Materias:	Animal Viruses
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109764/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9658066/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.8.6283-6290.1998
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