Attenuation of Influenza A Virus mRNA Levels by Promoter Mutations
We have engineered influenza A/WSN/33 viruses which have viral RNA (vRNA) segments with altered base pairs in the conserved double-stranded region of their vRNA promoters. The mutations were introduced into the segment coding for the neuraminidase (NA) by using a reverse genetics system. Two of the...
Uloženo v:
| Vydáno v: | J Virol |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology (ASM)
1998
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109764/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9658066/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.8.6283-6290.1998 |
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