Interferon Resistance of Hepatitis C Virus Genotype 1b: Relationship to Nonstructural 5A Gene Quasispecies Mutations

A 40-amino-acid sequence located in the nonstructural 5A (NS5A) protein of hepatitis C virus genotype 1b (HCV-1b) was recently suggested to be the interferon sensitivity-determining region (ISDR), because HCV-1b strains with an ISDR amino acid sequence identical to that of the prototype strain HCV-J...

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Pubblicato in:	J Virol
Autori principali:	Pawlotsky, Jean-Michel, Germanidis, Georgios, Neumann, Avidan U., Pellerin, Muriel, Frainais, Pierre-Olivier, Dhumeaux, Daniel
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Virus-Cell Interactions
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109724/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9525599/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.4.2795-2805.1998
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