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Interferon Resistance of Hepatitis C Virus Genotype 1b: Relationship to Nonstructural 5A Gene Quasispecies Mutations

A 40-amino-acid sequence located in the nonstructural 5A (NS5A) protein of hepatitis C virus genotype 1b (HCV-1b) was recently suggested to be the interferon sensitivity-determining region (ISDR), because HCV-1b strains with an ISDR amino acid sequence identical to that of the prototype strain HCV-J...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Pawlotsky, Jean-Michel, Germanidis, Georgios, Neumann, Avidan U., Pellerin, Muriel, Frainais, Pierre-Olivier, Dhumeaux, Daniel
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109724/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9525599/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.4.2795-2805.1998
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