Mutations in Rotavirus Nonstructural Glycoprotein NSP4 Are Associated with Altered Virus Virulence

Rotaviruses are major pathogens causing life-threatening dehydrating gastroenteritis in children and animals. One of the nonstructural proteins, NSP4 (encoded by gene 10), is a transmembrane, endoplasmic reticulum-specific glycoprotein. Recently, our laboratory has shown that NSP4 causes diarrhea in...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Zhang, Mingdong, Zeng, Carl Q.-Y., Dong, Yanjie, Ball, Judith M., Saif, Linda J., Morris, Andrew P., Estes, Mary K.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Viral Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109587/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9557647/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.5.3666-3672.1998
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