Diarrhea-Inducing Activity of Avian Rotavirus NSP4 Glycoproteins, Which Differ Greatly from Mammalian Rotavirus NSP4 Glycoproteins in Deduced Amino Acid Sequence, in Suckling Mice

Avian rotavirus NSP4 glycoproteins expressed in Escherichia coli acted as enterotoxins in suckling mice, as did mammalian rotavirus NSP4 glycoproteins, despite great differences in the amino acid sequences. The enterotoxin domain of PO-13 NSP4 exists in amino acid residues 109 to 135, a region simil...

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Detalhes bibliográficos
Main Authors: Mori, Yoshio, Borgan, Mohammed Ali, Ito, Naoto, Sugiyama, Makoto, Minamoto, Nobuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC137017/
https://ncbi.nlm.nih.gov/pubmed/11992013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.11.5829-5834.2002
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