Diarrhea-Inducing Activity of Avian Rotavirus NSP4 Glycoproteins, Which Differ Greatly from Mammalian Rotavirus NSP4 Glycoproteins in Deduced Amino Acid Sequence, in Suckling Mice

Avian rotavirus NSP4 glycoproteins expressed in Escherichia coli acted as enterotoxins in suckling mice, as did mammalian rotavirus NSP4 glycoproteins, despite great differences in the amino acid sequences. The enterotoxin domain of PO-13 NSP4 exists in amino acid residues 109 to 135, a region simil...

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Autores principales: Mori, Yoshio, Borgan, Mohammed Ali, Ito, Naoto, Sugiyama, Makoto, Minamoto, Nobuyuki
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC137017/
https://ncbi.nlm.nih.gov/pubmed/11992013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.11.5829-5834.2002
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