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NSP4 Enterotoxin of Rotavirus Induces Paracellular Leakage in Polarized Epithelial Cells

The nonstructural NSP4 protein of rotavirus has been described as the first viral enterotoxin. In this study we have examined the effect of NSP4 on polarized epithelial cells (MDCK-1) grown on permeable filters. Apical but not basolateral administration of NSP4 was found to cause a reduction in the...

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Detalhes bibliográficos
Main Authors: Tafazoli, Farideh, Zeng, Carl Q., Estes, Mary K., Magnusson, Karl-Erik, Svensson, Lennart
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114059/
https://ncbi.nlm.nih.gov/pubmed/11152526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.3.1540-1546.2001
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