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NSP4 Enterotoxin of Rotavirus Induces Paracellular Leakage in Polarized Epithelial Cells

The nonstructural NSP4 protein of rotavirus has been described as the first viral enterotoxin. In this study we have examined the effect of NSP4 on polarized epithelial cells (MDCK-1) grown on permeable filters. Apical but not basolateral administration of NSP4 was found to cause a reduction in the...

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Détails bibliographiques
Auteurs principaux: Tafazoli, Farideh, Zeng, Carl Q., Estes, Mary K., Magnusson, Karl-Erik, Svensson, Lennart
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2001
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC114059/
https://ncbi.nlm.nih.gov/pubmed/11152526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.3.1540-1546.2001
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