The rotavirus enterotoxin NSP4 mobilizes intracellular calcium in human intestinal cells by stimulating phospholipase C-mediated inositol 1,4,5-trisphosphate production

Rotavirus infection is the leading cause of severe diarrhea in infants and young children worldwide. The rotavirus nonstructural protein NSP4 acts as a viral enterotoxin to induce diarrhea and causes Ca(2+)-dependent transepithelial Cl(−) secretion in young mice. The cellular basis of this phenomeno...

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Cyhoeddwyd yn:	Proc Natl Acad Sci U S A
Prif Awduron:	Dong, Yanjie, Zeng, Carl Q.-Y., Ball, Judith M., Estes, Mary K., Morris, Andrew P.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	National Academy of Sciences 1997
Pynciau:	Biological Sciences
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20550/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9108087/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.8.3960
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