Inactivation of DNA-Dependent Protein Kinase by Protein Kinase Cδ: Implications for Apoptosis

Protein kinase Cδ (PKCδ) is proteolytically cleaved and activated at the onset of apoptosis induced by DNA-damaging agents, tumor necrosis factor, and anti-Fas antibody. A role for PKCδ in apoptosis is supported by the finding that overexpression of the catalytic fragment of PKCδ (PKCδ CF) in cells...

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Bibliographic Details
Main Authors: Bharti, Ajit, Kraeft, Stine-Kathrein, Gounder, Mrinal, Pandey, Pramod, Jin, Shengfang, Yuan, Zhi-Min, Lees-Miller, Susan P., Weichselbaum, Ralph, Weaver, David, Chen, Lan Bo, Kufe, Donald, Kharbanda, Surender
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC109255/
https://ncbi.nlm.nih.gov/pubmed/9774685
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