Inactivation of DNA-Dependent Protein Kinase by Protein Kinase Cδ: Implications for Apoptosis

Protein kinase Cδ (PKCδ) is proteolytically cleaved and activated at the onset of apoptosis induced by DNA-damaging agents, tumor necrosis factor, and anti-Fas antibody. A role for PKCδ in apoptosis is supported by the finding that overexpression of the catalytic fragment of PKCδ (PKCδ CF) in cells...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Bharti, Ajit, Kraeft, Stine-Kathrein, Gounder, Mrinal, Pandey, Pramod, Jin, Shengfang, Yuan, Zhi-Min, Lees-Miller, Susan P., Weichselbaum, Ralph, Weaver, David, Chen, Lan Bo, Kufe, Donald, Kharbanda, Surender
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1998
Schlagworte:	Cell Growth and Development
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109255/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9774685/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.11.6719
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