Substitution of the Human β-Spectrin Promoter for the Human (A)γ-Globin Promoter Prevents Silencing of a Linked Human β-Globin Gene in Transgenic Mice
During development, changes occur in both the sites of erythropoiesis and the globin genes expressed at each developmental stage. Previous work has shown that high-level expression of human β-like globin genes in transgenic mice requires the presence of the locus control region (LCR). Models of hemo...
Kaydedildi:
| Yayımlandı: | Mol Cell Biol |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Taylor & Francis
1998
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109248/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9774678/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.11.6634 |
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