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Substitution of the Human β-Spectrin Promoter for the Human (A)γ-Globin Promoter Prevents Silencing of a Linked Human β-Globin Gene in Transgenic Mice
During development, changes occur in both the sites of erythropoiesis and the globin genes expressed at each developmental stage. Previous work has shown that high-level expression of human β-like globin genes in transgenic mice requires the presence of the locus control region (LCR). Models of hemo...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC109248/ https://ncbi.nlm.nih.gov/pubmed/9774678 |
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