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The glucocorticoid receptor blocks P-TEFb recruitment by NFκB to effect promoter-specific transcriptional repression
To investigate the determinants of promoter-specific gene regulation by the glucocorticoid receptor (GR), we compared the composition and function of regulatory complexes at two NFκB-responsive genes that are differentially regulated by GR. Transcription of the IL-8 and IκBα genes is stimulated by T...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1091745/ https://ncbi.nlm.nih.gov/pubmed/15879558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1297105 |
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