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Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts

Members of the mammalian p160 family, such as GRIP1, are known as glucocorticoid receptor (GR) coactivators; at certain glucocorticoid response elements (GREs), however, GRIP1 acts as a GR corepressor. We characterized functional interactions of GR and GRIP1 in a repression complex where GR tethers...

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Detalhes bibliográficos
Main Authors: Rogatsky, Inez, Luecke, Hans F., Leitman, Dale C., Yamamoto, Keith R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC139207/
https://ncbi.nlm.nih.gov/pubmed/12481024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.262671599
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