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Alternate surfaces of transcriptional coregulator GRIP1 function in different glucocorticoid receptor activation and repression contexts

Members of the mammalian p160 family, such as GRIP1, are known as glucocorticoid receptor (GR) coactivators; at certain glucocorticoid response elements (GREs), however, GRIP1 acts as a GR corepressor. We characterized functional interactions of GR and GRIP1 in a repression complex where GR tethers...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Rogatsky, Inez, Luecke, Hans F., Leitman, Dale C., Yamamoto, Keith R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139207/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12481024/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.262671599
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