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The glucocorticoid receptor blocks P-TEFb recruitment by NFκB to effect promoter-specific transcriptional repression

To investigate the determinants of promoter-specific gene regulation by the glucocorticoid receptor (GR), we compared the composition and function of regulatory complexes at two NFκB-responsive genes that are differentially regulated by GR. Transcription of the IL-8 and IκBα genes is stimulated by T...

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Bibliografiske detaljer
Main Authors: Luecke, Hans F., Yamamoto, Keith R.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1091745/
https://ncbi.nlm.nih.gov/pubmed/15879558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1297105
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