Tumor Promoter Arsenite Activates Extracellular Signal-Regulated Kinase through a Signaling Pathway Mediated by Epidermal Growth Factor Receptor and Shc

Although arsenite is an established carcinogen, the mechanisms underlying its tumor-promoting properties are poorly understood. Previously, we reported that arsenite treatment leads to the activation of the extracellular signal-regulated kinase (ERK) in rat PC12 cells through a Ras-dependent pathway...

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Autores principales: Chen, Wei, Martindale, Jennifer L., Holbrook, Nikki J., Liu, Yusen
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1998
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC109103/
https://ncbi.nlm.nih.gov/pubmed/9710602
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