Requirement for Both Shc and Phosphatidylinositol 3′ Kinase Signaling Pathways in Polyomavirus Middle T-Mediated Mammary Tumorigenesis

Transgenic mice expressing the polyomavirus (PyV) middle T antigen (MT) develop multifocal mammary tumors which frequently metastasize to the lung. The potent transforming activity of PyV MT is correlated with its capacity to activate and associate with a number of signaling molecules, including the...

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Detalhes bibliográficos
Main Authors: Webster, Marc A., Hutchinson, John N., Rauh, Michael J., Muthuswamy, Senthil K., Anton, Martina, Tortorice, Christopher G., Cardiff, Robert D., Graham, Frank L., Hassell, John A., Muller, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC121489/
https://ncbi.nlm.nih.gov/pubmed/9528804
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