Requirement for Both Shc and Phosphatidylinositol 3′ Kinase Signaling Pathways in Polyomavirus Middle T-Mediated Mammary Tumorigenesis

Transgenic mice expressing the polyomavirus (PyV) middle T antigen (MT) develop multifocal mammary tumors which frequently metastasize to the lung. The potent transforming activity of PyV MT is correlated with its capacity to activate and associate with a number of signaling molecules, including the...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Webster, Marc A., Hutchinson, John N., Rauh, Michael J., Muthuswamy, Senthil K., Anton, Martina, Tortorice, Christopher G., Cardiff, Robert D., Graham, Frank L., Hassell, John A., Muller, William J.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1998
Schlagworte:	Cell Growth and Development
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121489/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9528804/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.4.2344
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