Distinct Roles of RAG1 and RAG2 in Binding the V(D)J Recombination Signal Sequences

The RAG1 and RAG2 proteins initiate V(D)J recombination by introducing double-strand breaks at the border between a recombination signal sequence (RSS) and a coding segment. To understand the distinct functions of RAG1 and RAG2 in signal recognition, we have compared the DNA binding activities of RA...

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izdano v:	Mol Cell Biol
Principais autores:	Akamatsu, Yoshiko, Oettinger, Marjorie A.
Format:	Artigo
Jezik:	Inglês
Izdano:	Taylor & Francis 1998
Teme:	DNA Dynamics and Chromosome Structure
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109053/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9671477/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.8.4670
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