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Distinct Roles of RAG1 and RAG2 in Binding the V(D)J Recombination Signal Sequences

The RAG1 and RAG2 proteins initiate V(D)J recombination by introducing double-strand breaks at the border between a recombination signal sequence (RSS) and a coding segment. To understand the distinct functions of RAG1 and RAG2 in signal recognition, we have compared the DNA binding activities of RA...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Akamatsu, Yoshiko, Oettinger, Marjorie A.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1998
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109053/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9671477/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.8.4670
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