Novel Mechanisms of E2F Induction by BK Virus Large-T Antigen: Requirement of Both the pRb-Binding and the J Domains

E2F activity is regulated in part by the retinoblastoma family of tumor suppressor proteins. Viral oncoproteins, such as simian virus 40 (SV40) large-T antigen (TAg), adenovirus E1A, and human papillomavirus E7, can disrupt the regulation of cellular proliferation by binding to pRb family members an...

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Bibliografische Detailangaben

Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Harris, Kimya F., Christensen, Joan B., Radany, Eric H., Imperiale, Michael J.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1998
Schlagworte:	Cell Growth and Development
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108889/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9488491/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.3.1746
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