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Novel Mechanisms of E2F Induction by BK Virus Large-T Antigen: Requirement of Both the pRb-Binding and the J Domains

E2F activity is regulated in part by the retinoblastoma family of tumor suppressor proteins. Viral oncoproteins, such as simian virus 40 (SV40) large-T antigen (TAg), adenovirus E1A, and human papillomavirus E7, can disrupt the regulation of cellular proliferation by binding to pRb family members an...

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書目詳細資料
發表在:Mol Cell Biol
Principais autores: Harris, Kimya F., Christensen, Joan B., Radany, Eric H., Imperiale, Michael J.
格式: Artigo
語言:Inglês
出版: Taylor & Francis 1998
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108889/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9488491/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.3.1746
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