Wordt geladen...

The Physical Association of Multiple Molecular Chaperone Proteins with Mutant p53 Is Altered by Geldanamycin, an hsp90-Binding Agent

Wild-type p53 is a short-lived protein which turns over very rapidly via selective proteolysis in the ubiquitin-proteasome pathway. Most p53 mutations, however, encode for protein products which display markedly increased intracellular levels and are associated with positive tumor-promoting activity...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Whitesell, Luke, Sutphin, Patrick D., Pulcini, Elizabeth J., Martinez, Jesse D., Cook, Paul H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 1998
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC108866/
https://ncbi.nlm.nih.gov/pubmed/9488468
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!