Regulation of Hypoxia-Inducible mRNAs by the von Hippel-Lindau Tumor Suppressor Protein Requires Binding to Complexes Containing Elongins B/C and Cul2

The von Hippel-Lindau tumor suppressor protein (pVHL) binds to elongins B and C and posttranscriptionally regulates the accumulation of hypoxia-inducible mRNAs under normoxic (21% O(2)) conditions. Here we report that pVHL binds, via elongin C, to the human homolog of the Caenorhabditis elegans Cul2...

Cijeli opis

Bibliografski detalji

Izdano u:	Mol Cell Biol
Glavni autori:	Lonergan, Kim M., Iliopoulos, Othon, Ohh, Michael, Kamura, Takumi, Conaway, Ronald C., Conaway, Joan Weliky, Kaelin, William G.
Format:	Artigo
Jezik:	Inglês
Izdano:	Taylor & Francis 1998
Teme:	Transcriptional Regulation
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108784/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9447969/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.2.732
Oznake:	Dodaj oznaku Bez oznaka, Budi prvi tko označuje ovaj zapis!