Regulation of the Deubiquitinating Enzyme CYLD by IκB Kinase Gamma-Dependent Phosphorylation

Tumor suppressor CYLD is a deubiquitinating enzyme (DUB) that inhibits the ubiquitination of key signaling molecules, including tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2). However, how the function of CYLD is regulated remains unknown. Here we provide evidence that inducible ph...

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Bibliographische Detailangaben
Hauptverfasser: Reiley, William, Zhang, Minying, Wu, Xuefeng, Granger, Erica, Sun, Shao-Cong
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087725/
https://ncbi.nlm.nih.gov/pubmed/15870263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.10.3886-3895.2005
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