Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice

Osteoclastogenesis is a tightly regulated biological process, and deregulation can lead to severe bone disorders such as osteoporosis. The regulation of osteoclastic signaling is incompletely understood, but ubiquitination of TNF receptor–associated factor 6 (TRAF6) has recently been shown to be imp...

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Detalhes bibliográficos
Main Authors: Jin, Wei, Chang, Mikyoung, Paul, Emmanuel M., Babu, Geetha, Lee, Andrew J., Reiley, William, Wright, Ato, Zhang, Minying, You, Jun, Sun, Shao-Cong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2276399/
https://ncbi.nlm.nih.gov/pubmed/18382763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34257
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