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Regulation of IκB Kinase-related Kinases and Antiviral Responses by Tumor Suppressor CYLD

The IκB kinase (IKK)-related kinases, IKKε and TBK1, participate in the induction of type I interferons (IFNs) during viral infections. Deregulated activation of IKKε and TBK1 also contributes to the abnormal cell survival and transformation. However, how these kinases are negatively regulated remai...

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Detalles Bibliográficos
Main Authors: Zhang, Minying, Wu, Xuefeng, Lee, Andrew J., Jin, Wei, Chang, Mikyoung, Wright, Ato, Imaizumi, Tadaatsu, Sun, Shao-Cong
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441564/
https://ncbi.nlm.nih.gov/pubmed/18467330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801451200
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