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Misregulation of 2μm Circle Copy Number in a SUMO Pathway Mutant

Attachment of the ubiquitin-like protein SUMO to other proteins is an essential process in Saccharomyces cerevisiae. However, yeast mutants lacking the SUMO ligases Siz1 and Siz2/Nfi1 are viable, even though they show dramatically reduced levels of SUMO conjugation. This siz1Δ siz2Δ double mutant is...

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Detalles Bibliográficos
Main Authors: Chen, Xiaole L., Reindle, Alison, Johnson, Erica S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087719/
https://ncbi.nlm.nih.gov/pubmed/15870299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.10.4311-4320.2005
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