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Recombination at Long Mutant Telomeres Produces Tiny Single- and Double-Stranded Telomeric Circles

Recombinational telomere elongation (RTE) known as alternate lengthening of telomeres is the mechanism of telomere maintenance in up to 5 to 10% of human cancers. The telomeres of yeast mutants lacking telomerase can also be maintained by recombination. Previously, we proposed the roll-and-spread mo...

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Main Authors: Groff-Vindman, Cindy, Cesare, Anthony J., Natarajan, Shobhana, Griffith, Jack D., McEachern, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140610/
https://ncbi.nlm.nih.gov/pubmed/15899847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.11.4406-4412.2005
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