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Evolution and the molecular basis of somatic hypermutation of antigen receptor genes.
Somatic hypermutation of immunoglobulin genes occurs in many vertebrates including sharks, frogs, camels, humans and mice. Similarities among species reveal a common mechanism and these include the AGC/T sequence hot spot, preponderance of base substitutions, a bias towards transitions and strand bi...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1087693/ https://ncbi.nlm.nih.gov/pubmed/11205333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2000.0750 |
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