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Paclitaxel (Taxol)-Induced Killing of Leishmania major in Murine Macrophages

The antitumor drug paclitaxel (Taxol) has been demonstrated to be a lipopolysaccharide mimetic in murine macrophages. In this study, the capacity of paclitaxel to activate macrophages to become microbicidal for Leishmania major was examined. Paclitaxel and gamma interferon synergized to kill intrace...

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Detalhes bibliográficos
Main Authors: Doherty, T. Mark, Sher, Alan, Vogel, Stefanie N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC108557/
https://ncbi.nlm.nih.gov/pubmed/9712819
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