Paclitaxel (Taxol)-Induced Killing of Leishmania major in Murine Macrophages

The antitumor drug paclitaxel (Taxol) has been demonstrated to be a lipopolysaccharide mimetic in murine macrophages. In this study, the capacity of paclitaxel to activate macrophages to become microbicidal for Leishmania major was examined. Paclitaxel and gamma interferon synergized to kill intrace...

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Pubblicato in:	Infect Immun
Autori principali:	Doherty, T. Mark, Sher, Alan, Vogel, Stefanie N.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Fungal and Parasitic Infections
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108557/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9712819/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.9.4553-4556.1998
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