Paromomycin and Geneticin Inhibit Intracellular Cryptosporidium parvum without Trafficking through the Host Cell Cytoplasm: Implications for Drug Delivery

Cryptosporidium parvum, which causes intractable diarrhea and lethal wasting in people with AIDS, occupies an unusual intracellular but extracytoplasmic niche. No reliable therapy for cryptosporidiosis exists, though the aminoglycoside paromomycin is somewhat effective. We report that paromomycin an...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Griffiths, Jeffrey K., Balakrishnan, Ramaswamy, Widmer, Giovanni, Tzipori, Saul
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Molecular and Cellular Pathogenesis
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108441/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9673275/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.8.3874-3883.1998
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