Paromomycin and Geneticin Inhibit Intracellular Cryptosporidium parvum without Trafficking through the Host Cell Cytoplasm: Implications for Drug Delivery

Cryptosporidium parvum, which causes intractable diarrhea and lethal wasting in people with AIDS, occupies an unusual intracellular but extracytoplasmic niche. No reliable therapy for cryptosporidiosis exists, though the aminoglycoside paromomycin is somewhat effective. We report that paromomycin an...

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Detaylı Bibliyografya

Yayımlandı:	Infect Immun
Asıl Yazarlar:	Griffiths, Jeffrey K., Balakrishnan, Ramaswamy, Widmer, Giovanni, Tzipori, Saul
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Microbiology (ASM) 1998
Konular:	Molecular and Cellular Pathogenesis
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108441/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9673275/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.8.3874-3883.1998
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