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The de novo methylation activity of Dnmt3a is distinctly different than that of Dnmt1

BACKGROUND: Though Dnmt1 is considered the primary maintenance methyltransferase and Dnmt3a and Dnmt3b are considered de novo methyltransferases in mammals, these three enzymes may work together in maintaining as well as establishing DNA methylation patterns. It has been proposed that Dnmt1 may carr...

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Detalhes bibliográficos
Autor principal: Hsieh, Chih-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084342/
https://ncbi.nlm.nih.gov/pubmed/15799776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-6-6
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