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The de novo methylation activity of Dnmt3a is distinctly different than that of Dnmt1

BACKGROUND: Though Dnmt1 is considered the primary maintenance methyltransferase and Dnmt3a and Dnmt3b are considered de novo methyltransferases in mammals, these three enzymes may work together in maintaining as well as establishing DNA methylation patterns. It has been proposed that Dnmt1 may carr...

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Hlavní autor: Hsieh, Chih-Lin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084342/
https://ncbi.nlm.nih.gov/pubmed/15799776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-6-6
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