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Recql5 and Blm RecQ DNA Helicases Have Nonredundant Roles in Suppressing Crossovers

In eukaryotes, crossovers in mitotic cells can have deleterious consequences and therefore must be suppressed. Mutations in BLM give rise to Bloom syndrome, a disease that is characterized by an elevated rate of crossovers and increased cancer susceptibility. However, simple eukaryotes such as Sacch...

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Detalhes bibliográficos
Main Authors: Hu, Yiduo, Lu, Xincheng, Barnes, Ellen, Yan, Min, Lou, Hua, Luo, Guangbin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084310/
https://ncbi.nlm.nih.gov/pubmed/15831450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.9.3431-3442.2005
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