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Recql5 and Blm RecQ DNA Helicases Have Nonredundant Roles in Suppressing Crossovers
In eukaryotes, crossovers in mitotic cells can have deleterious consequences and therefore must be suppressed. Mutations in BLM give rise to Bloom syndrome, a disease that is characterized by an elevated rate of crossovers and increased cancer susceptibility. However, simple eukaryotes such as Sacch...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1084310/ https://ncbi.nlm.nih.gov/pubmed/15831450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.9.3431-3442.2005 |
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