Cyclins D2 and D1 Are Essential for Postnatal Pancreatic β-Cell Growth

Regulation of adult β-cell mass in pancreatic islets is essential to preserve sufficient insulin secretion in order to appropriately regulate glucose homeostasis. In many tissues mitogens influence development by stimulating D-type cyclins (D1, D2, or D3) and activating cyclin-dependent kinases (CDK...

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Autori principali: Kushner, Jake A., Ciemerych, Maria A., Sicinska, Ewa, Wartschow, Lynn M., Teta, Monica, Long, Simon Y., Sicinski, Piotr, White, Morris F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
Soggetti:
Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084308/
https://ncbi.nlm.nih.gov/pubmed/15831479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.9.3752-3762.2005
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