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Essential Role for Cyclin D3 in Granulocyte Colony-Stimulating Factor-Driven Expansion of Neutrophil Granulocytes

The proliferation of neutrophil granulocyte lineage is driven largely by granulocyte colony-stimulating factor (G-CSF) acting via the G-CSF receptors. In this study, we show that mice lacking cyclin D3, a component of the core cell cycle machinery, are refractory to stimulation by the G-CSF. Consequ...

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Detalhes bibliográficos
Main Authors: Sicinska, Ewa , Lee, Young-Mi, Gits, Judith, Shigematsu, Hirokazu, Yu, Qunyan, Rebel, Vivienne I., Geng, Yan, Marshall, Christopher J., Akashi, Koichi, Dorfman, David M., Touw, Ivo P., Sicinski, Piotr
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636755/
https://ncbi.nlm.nih.gov/pubmed/16954383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00800-06
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