Hypoxia-inducible factor-1α (HIF-1α) escapes O(2)-driven proteasomal degradation irrespective of its subcellular localization: nucleus or cytoplasm

Eukaryotic cells sense oxygen and adapt to hypoxia by regulating a number of genes. Hypoxia-inducible factor 1 (HIF-1) is the ‘master’ in this pleiotypic response. HIF-1 comprises two members of the basic helix–loop–helix transcription factor family, HIF-1α and HIF-1β. The HIF-1α protein is subject...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Berra, Edurne, Roux, Danièle, Richard, Darren E., Pouysségur, Jacques
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2001
Pynciau:
Scientific Reports
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083944/
https://ncbi.nlm.nih.gov/pubmed/11454738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve130
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